Distribution: Single or multiple (every 28 days) 5-minute or 15-minute infusions of 2, 4, 8, or 16 mg zoledronic acid were given to 64 patients with cancer and bone metastases
Comment: For the Cataract Removal with IOL Implantation measure we proposed, one commenter recommended excluding episodes for patients with a history of herpes and zoster virus, retinal degeneration, anterior scleritis, posterior polar cataracts, recurrent corneal erosions, punctate keratitis, neurotrophic keratitis, exposure keratoconjunctivitis, filamentary keratitis, lagophthalmos, and exophthalmic conditions to account for high-cost conditions that could be outside a clinician's control
Note on the tolerance/diminishing-effect claim: the widely repeated effect fades after 4 to 6 weeks figure appears as repeated online claims, not in any primary study I could locate
In some cases, patients experience numbness and weakness
Common B12 deficiency symptoms include: Persistent fatigue and weakness Tingling or numbness in hands and feet Memory problems and difficulty concentrating Mood changes like irritability or depression Dizziness and balance issues Pale skin or yellowing of eyes Sore, red tongue Who is Most at Risk for B12 Deficiency
Thus, we solicited comment on whether these coordination and referral services typically occur during SUD counseling session services, or if they may occur during initial or periodic assessments, therapy sessions, or as part of other services